CagA status and VacA subtypes ofHelicobacter pyloriin relation to histopathologic findings in Iranian population
نویسندگان
چکیده
منابع مشابه
Helicobacter pylori cagA Status, vacA Subtypes and Histopathologic Findings in Iranian Patients with chronic gastritis
Background and Objective: Helicobacter pylori has several strains with different degrees of virulence. The aim of this study was to detect two major important virulence factors, cagA/vacA genotypes, and to determine correlations among different cagA/vacA genotypes and histological features of chronic gastritis in Iranian patients. Methods: In this cross- sectional study, Gastric bi...
متن کاملhelicobacter pylori caga status, vaca subtypes and histopathologic findings in iranian patients with chronic gastritis
background and objective: helicobacter pylori has several strains with different degrees of virulence. the aim of this study was to detect two major important virulence factors, caga/vaca genotypes, and to determine correlations among different caga/vaca genotypes and histological features of chronic gastritis in iranian patients. methods: in this cross- sectional study, gastric biopsy was take...
متن کاملvacA genotypes of Helicobacter pylori in relation to cagA status and clinical outcomes in Iranian populations.
Mosaicism in vacA alleles with two distinct families of vacA signal sequences (s1 and s2) and two distinct families of middle region alleles (m1 and m2) has been reported. Research suggests that the vacA s1 genotype is closely associated with duodenal ulcer disease and with high cytotoxin production. The aims of this study were to evaluate the role of vacA genotyping with respect to gastric inf...
متن کاملAssociation between Helicobacter pylori, cagA, and vacA Status and Clinical Presentation in Iranian Children
OBJECTIVE Seroprevalence of H. pylori infection in Iran exceeds 65% of pediatric population. In this study, we intended to find association between the virulence genes (cagA and vacA) and clinical presentations. METHODS H. pylori isolates were achieved from the gastric mucosa of children. In each case, the gastric biopsy specimens were cultured and the organisms identified. Detection of diffe...
متن کاملcagA and vacA status of Spanish Helicobacter pylori clinical isolates.
Helicobacter pylori is a gram-negative rod associated with gastroduodenal pathologies, such as gastritis, peptic ulcer, and gastric adenocarcinoma. Although most H. pylori infections are clinically silent, the organism is associated with substantial morbidity and mortality. It is unknown why the bacteria are able to produce severe disease in some hosts and be innocuous in others. Different viru...
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ژورنال
عنوان ژورنال: Indian Journal of Pathology and Microbiology
سال: 2010
ISSN: 0377-4929
DOI: 10.4103/0377-4929.59178